EAGAN, Minn. — Kyler Murray will be sidelined for the Vikings Monday Night Football game with a hamstring strain, Head Coach Kevin O'Connell said Thursday.

O'Connell announced Carson Wentz will start the prime-time contest in Murray's place. Max Brosmer will be Minnesota's backup quarterback.

"After evaluating Kyler on Monday, getting some imagery and things, we did determine he does have a hamstring strain," O'Connell said. "We don't believe it to be more than a week-to-week kind of thing right now, but for him, his movement skills and the way he plays the game, we do feel like we'd be putting him at risk of possibly turning this into a more significant injury than it is by trying to have him work through it here early on.

"Obviously there's a ton of confidence in Carson," O'Connell added. "He's already helped us — had a major role in two wins this year against two really good teams. He's a steady presence and a guy we know."

Wentz replaced Murray in Week 1 after the first-year Viking left the game early in concussion protocol and helped Minnesota mount a comeback victory against Green Bay. He started the following week at rain-soaked Chicago, helping Minnesota open with consecutive division wins.

Murray returned to the lineup in Week 3 and has started and played the entirety of the past five games.

The Vikings (6-1) are following an adjusted schedule in advance of Monday's game against the Bills (6-1) and will practice Thursday, Friday and Saturday.

In addition to the quarterback update, O'Connell noted safety Theo Jackson (quad) will not participate in Thursday's practice. Left tackle Christian Darrisaw will practice.

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