Dalvin Cook will undergo an MRI on Monday, Vikings Head Coach Mike Zimmer said.
Zimmer didn't have much of an update other than to say the Vikings running back will be evaluated Monday.
"I don't know, I haven't heard anything yet," Zimmer said. "We'll get an MRI."
Zimmer added that he doesn't know if Cook's injury will be season-ending.
Cook suffered the injury late in the third quarter and left the game after a scary play.
The running back was tackled for a loss of 4 yards and fumbled, but he was shaken up after the play and had to leave the game on a cart.
Cook, who was ruled out with a shoulder injury, was attended to by trainers and encouraged by players on both teams as he left the field.
Vikings wide receiver Justin Jefferson and quarterback Kirk Cousins each said they hope the best for their teammate.
"I know Dalvin is going to bounce back," Jefferson said. "We don't know how serious that injury is, but [we're] just keeping him in our prayers and hopefully he's OK and comes back for us."
Cousins added: "You just hate to see him go down and get carted off and see the pain that he was in. That's tough to see that from a teammate like Dalvin. [That's] someone … such a key piece of our team and our offense."
Zimmer said rookie Kene Nwangwu, who had a 99-yard kickoff return for a score, could be more involved offensively going forward.
"Yeah, I think there's a chance that he may end up getting some more playing time," Zimmer said. "He got a couple carries today, I think.
"He's still a young guy, and we brought him in as a kickoff returner and a backup running back, but he's done a nice job on a couple of these situations for returning the ball," Zimmer added.